The Apothecary Diaries Season 3 Confirmed for October 2, With a Yorushika Opening Theme

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The Apothecary Diaries fans finally have a date: Season 3 premieres October 2, confirmed alongside a new trailer, key visual, and opening theme announcement.

October 2, Split Into Two Cours

The new trailer, released August 15, confirmed the October 2, 2026 premiere for Season 3's first cour, with the second cour following in spring 2027. The trailer teases a new arc involving a potential famine tied to a legend about an "immortal maiden."

New Cast and a Yorushika Opening Theme

Reina Ueda joins the cast as a new character connected to that legend. The opening theme, "Kumo wo Nuke Kazashita e Watashi Dake," comes from Yorushika — the season continues to stream on Crunchyroll, as with previous seasons.

What To Know

Fans have been waiting for a confirmed Season 3 date since Season 2 wrapped, and now they have an exact one plus a specific new mystery hook to anticipate, rather than just a vague "coming later this year."

Yorushika is a good example of a now-common career path in Japanese music — an artist who built their early audience through Vocaloid-adjacent and independent releases before crossing over into major anime theme songs, the same arc TBM has already covered for artists like Kenshi Yonezu.

What Fans Are Saying

• "October 2 is circled on my calendar now, finally an actual date."
• "Yorushika for the OP is such a good pick, been waiting for them to do an anime theme this big."

Original Japanese

• 「10月2日、楽しみにしています」
• 「ヨルシカが主題歌なんて豪華すぎます」

Easy Japanese

『薬屋のひとりごと』第3期は10月2日から始まります。主題歌はヨルシカです。